Many women begin experiencing symptoms of pre or perimenopause several years before menopause occurs. The age when the signs of premenopause occur varies among women. Some women experience the symptoms of perimenopause in their early thirties, while other women may notice menopausal signs in their forties, and still other women never experience any changes during menopause. More

The clinical features of menopause are caused by the estrogen deficiency. Vasomotor instability, Urogenital atrophy, Skeletal, Skin, soft tissue, Psychological More

The cessation of menses is the result of the eventual atresia of almost all oocytes in the ovaries. This causes an increase in circulating FSH and LH levels as there are a decreased number of oocytes responding to these hormones and producing estrogen. This decrease in the production of estrogen leads to the post-menopausal symptoms of hot flashes, insomnia, osteoporosis, atherosclerosis, vaginal atrophy and depression. More

Menopause is the physiological cessation of menstrual cycles associated with advancing age in species that experience such cycles. Menopause is sometimes referred to as change of life or climacteric. Menopause occurs as the ovaries stop producing estrogen, causing the reproductive system to gradually shut down. As the body adapts to the changing levels of natural hormones, vasomotor symptoms such as hot flashes and palpitations, psychological symptoms such as increased depression, anxiety, irritability, mood swings and lack of concentration, and atrophic symptoms such as vaginal dryness and urgency of urination appear. Together with these symptoms, the woman may also have increasingly scanty and erratic menstrual periods. More